Klippel-Feil syndrome is a complex heterogeneous entity that results in cervical vertebral fusion. Two or more non-segmented cervical vertebrae are usually sufficient for diagnosis. Epidemiology There is a recognised female predilection 1 Klippel-Feil syndrome: CT and MR of acquired and congenital abnormalities of cervical spine and cord. We reviewed MR and CT myelographic studies in patients with the Klippel-Feil syndrome (KFS) to determine the patterns of associated congenital and acquired abnormalities of the spine and spinal cord and to correlate these radiologic findings with. Clinical: classic triad present in 50% of short neck, low hairline, restricted neck motion Cases of Klippel-Feil Syndrome AP radiograph of the cervical spine shows multiple segmentation anomalies including vertebral body fusion and hemivertebrae of the cervical spine and upper thoracic spine
Klippel-Feil syndrome is defined as congenital fusion of two or more cervical vertebrae. People with this syndrome who also have cervical stenosis may be at increased risk for spinal cord injury after minor trauma as a result of hypermobility The Klippel-Feil syndrome is a congenital anatomical defect in the neck, which includes fusion of two or more cervical vertebrae. This syndrome is also described as congenital brevicollis syndrome. Feil has classified this syndrome into 3 categories: Type I = A massive fusion of the cervical spin Klippel-Feil syndrome is a congenital malformation of the cervical spine in which two or more vertebrae are fused. It is most likely due to an abnormality in somatic segmentation. The term Klippel-Feil syndrome was originally used to describe the clinical triad of fused cervical vertebra, short neck and low posterior hairline; however, now the term is used more broadly for cervical fusion Klippel-Feil syndrome is characterized by congenital fusion of two or more cervical vertebrae and may be associated with other organ system anomalies. Although many congenital anomalies are of little clinical importance to the emergency physician, Klippel-Feil syndrome is associated with both sponta
Klippel-Feil syndrome, also known as cervical vertebral fusion syndrome, is a rare congenital condition characterized by the abnormal fusion of any two of the seven bones in the neck. It results in a limited ability to move the neck and shortness of the neck, resulting in the appearance of a low hairline. The syndrome is difficult to diagnose, as it occurs in a group of patients affected with many different abnormalities who can only be unified by the presence of fused or segmental. Klippel-Feil syndrome (KFS) is a complex syndrome of osseous and visceral anomalies that include the classical clinical triad of short neck, limitation of head and neck movements and low posterior hairline. It may also be associated with anomalies of the genitourinary, musculoskeletal, neurologic and cardiac systems Klippel-Feil syndrome (KFS) is a rare skeletal disorder primarily characterized by abnormal union or fusion of two or more bones of the spinal column (vertebrae) within the neck (cervical vertebrae) Klippel-Feil syndrome occurs in a heterogeneous group of patients unified only by the presence of a congenital defect in the formation or segmentation of the cervical spine. Numerous associated abnormalities of other organ systems may be present Klippel feil syndrome 1. Klippel-Feil syndrome Presented by MD. MONSUR RAHMAN 2. What is Klippel-Feil syndrome ? The Klippel-Feil syndrome is a congenital anatomical defect in the neck, which includes fusion of two or more cervical vertebrae. This syndrome is also described as congenital brevicollis syndrome Feil has classified this syndrome into 3 categories: Type I = A massive fusion of the.
Klippel-Feil Syndrome Diagnosis and Treatment Usually, Klippel-Feil Syndrome is diagnosed based on the classic triad of symptoms but sometimes it remains undiagnosed until later in life. Radiological examination consisting of X-rays, MRI and CT scan will reveal abnormal and defective vertebrae and associated tissues Klippel-Feil syndrome (KFS) is a rare genetic bone disorder where at least two vertebrae in the neck are fused together from birth. Due to this fusion, patients with KFS have limited neck mobility along with neck and back pain and often chronic headaches. 1 . The syndrome was first discovered in 1912 by French physicians Maurice Klippel and. Klippel-Feil syndrome is a bone disorder characterized by the abnormal joining of two or more spinal bones in the neck (cervical vertebrae).The vertebral fusion is present from birth. Three major features result from this vertebral fusion: a short neck, the resulting appearance of a low hairline at the back of the head, and a limited range of motion in the neck
The clinical presentation of Klippel-Feil syndrome (KFS; also referred to as cervical vertebral fusion syndrome) is varied because of the different associated syndromes and anomalies that can occur in patients with the syndrome. In children in particular, the classic clinical triad of manifestations (see Background) may not all be present Klippel-Feil syndrome (KFS) is a rare disorder characterized by the congenital fusion of cervical vertebrae [1-3] and affects anywhere from 1 in 40,000 to 50,000 live births [4, 20].KFS is a heterogeneous condition presenting with an array of skeletal/extra-skeletal manifestations [1, 4-9] and is best known for the classical syndromic triad, found in approximately 50 % of patients. Intervertebral Disc Calcification and Klippel-Feil Syndrome Case Report Justin Cole 1 *, Fadi Nemeh 1, Achint K Singh 1, Jason Lally 1 Radiology Case. 2020 Aug; 14(8):8-13 :: DOI: 10.3941/jrcr.v14i8.379 Pediatric Radiology Radiology Case. 2020 Aug; 14(8):8-13 : Intervertebral Disc Calcification and Klippel-Feil Syndrome Cole et al. J ou rna l of MR imaging typically have mixed signal characteristics R C as e Rep rts on MR imaging can be hypointense at both T1 and T2
KLIPPEL-FEIL syndrome presents with a short neck and severe restriction of cervical motion. 1 The accompanying magnetic resonance image demonstrates this neck deformity due to the fusion of cervical vertebrae (image A, arrow A) and severe central canal stenosis (image A, arrow B).A lateral cervical spine X-ray (image B) demonstrates cervical fusion (arrow A') but not the extent of spinal. Klippel-Feil syndrome is a congenital malformation characterized by the fusion of at least 2 cervical vertebrae. It may occur in association with other clinical syndromes and disorders. We describe a case of prenatal diagnosis of a Klippel-Feil syndrome with Dandy-Walker malformation, and spina bifida, proved by ultrasound examination Klippel-Feil syndrome Definition/Description. The Klippel-Feil syndrome is a congenital anatomical defect in the neck, which includes fusion... Epidemiology /Etiology. The klippel-feil syndrome is caused by a failure of segmentation of the cervical vertebrae... Characteristics/Clinical Presentation..
Klippel-Feil syndrome (KFS) is a congenital malformation causing fusion of at least two cervical vertebrae and characterized clinically by presence of triad of short neck, limited neck movements, and low posterior hair line. Various skeletal and non-skeletal anomalies may be seen in association with KFS. We present a case of 6-year-old boy of KFS with various skeletal anomalies such as. CONGENITAL brevicollis probably has been recognized since ancient times. Fused cervical vertebrae have been noted in an Egyptian mummy dating back to 500 bc, 1 and in bones of an ancient civilization uncovered in Paucarcancha, Peru. 2 The Acephala, a mythical race who supposedly lived in Western Libya, have been described as having heads planted directly on their chests. 3 Pictures of the.
We report on a 33 year old woman with Rothmund-Thompson syndrome, Klippel-Feil syndrome and osteosarcoma. We briefly discuss the relationship of these diseases and suggest that the cause for mental retardation is cerebral atrophy as shown on imaging Congenital abnormality of vertebral segmentation. Fusion of the vertebral bodies and posterior columns at C2/3 is the most common variant and causes a restriction of movement. Associated features include a short neck and a low posterior hairline Klippel-Feil Syndrome Peter D. Pizzutillo Martin J. Herman HISTORICAL BACKGROUND In 1912, Klippel and Feil published the clinical and anatomic description of L. Joseph, a 46-year-old tailor with a history of chronic abdominal pain and recurrent pleural effusions (1). His appearance was notable for an extremely short neck and a low hairline; physical examination reveale Klippel-Feil's Syndrome Associated with Compression of the Spinal Cord by an Extradural Hemangiolipoma. Paul C. Bucy M.D. 1 and Hardin Ritchey M.D. 1 View More View Less. 1 Department of Neurology and Neurological Surgery, University of Illinois College of Medicine, Radiology, 1945, 44: 79.
Klippel-Feil Syndrome is a rare disorder characterized by the congenital fusion of two or more cervical (neck) vertebrae. It is caused by a failure in the normal segmentation or division of the cervical vertebrae during the early weeks of fetal development. The most common signs of the disorder are short neck, low hairline at the back of the. Klippel-Feil syndrome is a clinical triad consisting of fusion of cervical (and sometimes other) vertebrae, with associated shortening of the neck, limited head motion, and a low posterior hairline. Most cases are sporadic, although autosomal dominant and autosomal recessive cases are recognized Firtina S, Mehmet AK. Klippel-Feil Syndrome and Thoracic Outlet Syndrome. Neurol Disord Epilepsy J. 2017; 1(1):113. Monophasic flow pattern showed b upper limbs, so the patient was diagnosed bilateral thoracic outlet syndrome additionally. The occurrence of thoracic outlet syndrome was thought to be the . Correspondence: Ali Rıza Sonkaya Klippel-Feil syndrome may also present as part of another disorder or syndrome, including Goldenhar syndrome, Wildervanck syndrome, hemifacial microsomia, or fetal alcohol syndrome. Inheritance in these cases is determined by the gene associated with the constellation of symptoms rather than with the KFS manifestations alone. 11 , 20 , 2 Klippel-Feil Syndrome Diagnosis and Treatment Usually, Klippel-Feil Syndrome is diagnosed based on the classic triad of symptoms but sometimes it remains undiagnosed until later in life. Radiological examination consisting of X-rays, MRI and CT scan will reveal abnormal and defective vertebrae and associated tissues
Klippel-Feil Syndrome is said to be caused due to mutations in genes GDF6 and GDF3. The function of these genes is to instruct cells into making proteins to regulate growth and maturation of the bones and cartilages in the body. The GDF6 protein is required for formation of bones in the limbs, spine, skull, chest, and ribs Klippel-Feil syndrome is a rare bone disorder distinguished by the abnormal fusion of two or more bones in the neck. Children with the disorder may have a short, webbed neck, decreased range of motion in the head and neck area, and fusions in the thoracic spine causing scoliosis and/or kyphosis. Klippel-Feil syndrome forms in utero when genes GDF6 or GDF3 mutate Features of bilateral Sprengel deformity with Klippel-Feil syndrome Sprengel deformity, or congenital elevation of the scapula, is the most common congenital deformity of the shoulder. The initial diagnosis can be made on simple radiography, how..
3 Reasons Why I Advocate for Klippel-Feil Syndrome. Klippel-Feil syndrome (KFS) is a rare skeletal condition. It is diagnosed when two or more of the seven vertebrae in the neck are fused together congenitally, or from birth. KFS is permanent and can be degenerative. Some patients with mild iterations of KFS may never experience significant. Klippel-Feil Syndrome Freedom. 4,881 likes · 40 talking about this. KFS Freedom empowers & unites patients & their families through peer support, education, research, & advocacy, for a lifetime of..
Klippel Feil syndrome (KFS) is a rare disease that affects the development of bones in the spine. According to the National Institute of Health, it's a congenital condition consisting of an abnormal fusion of at least two spinal bones.. People with Klippel Feil syndrome often have a shorter neck, a low hairline or restricted movement of the upper back Klippel Feil Syndrome (KFS) is defined as congenital anomaly with fusion of two or more cervical vertebral bodies characterized by presence of classic triad which includes low posterior hairline, short neck and restricted range of motion(1,2). Typical classic triad however is found only in about 50% of cases(3,4) Klippel-Feil Syndrome - Symptoms, Causes, Treatment, Life expectancy, Pictures and Photos. This syndrome is thought to occur very early in development of the fetus due to cervical Van Looveren, K, Filip Vanhoenacker, Geert Mortier, and PM Parizel. 2014. Klippel-Feil Syndrome. EuroRad.European Society of Radiology (ESR)
49. Klippel-Feil Syndrome Definition Klippel-Feil syndrome is a rare congenital disorder in which any two of the seven cervical vertebrae are absent or fused, resulting in a short neck with limited range of motion. Classification of Klippel-Feil Syndrome Type I Massive fusion of the cervical spine Type II Fusion of one or two cervical interspace Debra Durkee Date: January 25, 2021 There is a high occurrence of scoliosis among people with Klippel-Feil syndrome.. Klippel-Feil syndrome is a condition in which several of the vertebrae in the neck are fused together. This disorder develops in the early stages of a baby's development, usually in the first one to two months Klippel Feil syndrome (KPS) was first described by Maurice Klippel, a French internist and Andre Feil in a patient with congenital fusion of cervical vertebrae. Based on clinico radiological features it is classified into : Type 1 : Fusion of cervical and upper thoracic vertebrae with synostosis accounting for 40%
Klippel-Feil syndrome is defined as fusion of multiple cervical vertebrae. The condition was first reported in 1912 by Drs. Klippel and Feil when they described a patient with a short neck, low posterior hairline and restricted neck range of motion (Hensinger, 1974). These characteristics are considered to be the classic triad in this patient. Klippel-Feil syndrome is an uncommon anomaly that may be asymptomatic. Early clinical signs such as restricted neck motion or short neck can be subtle and incorrectly treated as spasms. and also sparsely known in radiology literature. We demonstrate the importance of computed tomography angiography in preprocedural planning to avoid. Treatment for Klippel-Feil syndrome depends on the severity of the condition and the other conditions that present. For some cases, self-care and nonsurgical treatment, like physical therapy and bracing may suffice. In others, surgery may be needed to stabilize the cervical spine or correct a deformity Klippel-Feil Syndrome Causes & Risk Factors. The specific cause of the Klippel-Feil Syndrome is, up to this point, unknown. However, there are studies that show that it may be a mixture of spontaneous mutation and genes. The persons at risk for this kind of syndrome are commonly reported in women
Background. Klippel-Feil syndrome (KFS) is characterised by congenital vertebral fusion of the cervical spine and a wide spectrum of associated anomalies. KFS has often been considered a sporadic syndrome. However, since the publication of the original KFS classification early this century, a number of KFS families have indicated heterogeneity complicated by a broad range of variable expression Klippel-Feil syndrome (KFS), also known as cervical vertebral fusion syndrome, is a rare congenital condition characterized by the abnormal fusion of any two of the seven bones in the neck (cervical vertebrae).: 578 It results in a limited ability to move the neck and shortness of the neck, resulting in the appearance of a low hairline Klippel Feil Syndrome: Klippel Feil Syndrome is a bone disorder characterized by the congenital spinal fusion of any two of the seven cervical vertebrae. The bone disorder present- the fused vertebra in the neck from the birth. Three significant features result from this fused vertebra in the neck: a short neck, a low hairline at the back of the head, and a limited range of movement in the neck Coexistence of Klippel-Feil syndrome with Sprengel deformity and omovertebral bone is a rare complex bone abnormality with unknown incidence and etiology. Herein, we report a case of a 6-year-old girl with coexistence of these congenita
Although commonly symptomatic, conservative management yields excellent prognosis in the vast majority of cases. The following case illustrates the finding of intervertebral disc calcification in a patient with vertebral body segmentation anomaly consistent with Klippel-Feil Syndrome Klippel-Feil Syndrome Freedom. 4,895 likes · 53 talking about this. KFS Freedom empowers & unites patients & their families through peer support, education, research, & advocacy, for a lifetime of..
Klippel-Feil syndrome-4 with nemaline myopathy and facial dysmorphism is an autosomal recessive disorder characterized mainly by severe hypotonia apparent from infancy. Klippel-Feil anomaly is primarily defined by fusion of the cervical spine, with associated low posterior hairline and limited neck mobility being observed in about half of. Klippel-Feil syndrome What is a Klippel-Feil syndrome? It is a musculoskeletal defect characterized by union of two vertebrae in the neck. KFS is a congenital and genetic in nature, which means that the patient has it at birth Deafness and the Klippel-Feil Syndrome By K. MCLA (EdinburghY ) and MARA A. G. (DundeeN D. ) THE association of deafness with the Klippel-Feil syndrome has been previously described and we here present 3 additional cases. In 2 of these, full clinical and radiological details are given while the third includes
El síndrome de Klippel-Feil es una rara enfermedad, reportada originalmente en 1912 por Maurice Klippel y André Feil, que se caracteriza por la fusión congénita de 2 de las 7 vértebras cervicales.De hecho, el síndrome de Klippel-Feil ocurre en un grupo heterogéneo de pacientes unificado solo por la presencia de un defecto congénito en la formación o la segmentación de la columna. Patients with Klippel-Feil syndrome (KFS; also referred to as cervical vertebral fusion syndrome) present at different ages with varying clinical manifestations. Indications for workup vary individually. Plain radiography is the basis for the diagnosis of KFS. Initial studies include anteroposterior (AP) and lateral views of the cervical spine. The authors conducted a study to identify radiological patterns of KlippelFeil syndrome (KFS), and they present a new interpretation of the origin of these patterns based on recent advances in understanding of embryonic development of the spine and its molecular genetic control Klippel Feil Syndrome. Poster un commentaire..rappelle qu'avant l'age de 13 rien n'était visible sur radio et irm c'est pour cela que le diagnostique a été tres long en espérant avoir une réponse amicalement nikie Répondre Signaler Cliquez ici pour acceder à l'article. Share this
Klippel-Feil syndrome is a rare congenital disorder in which any two of the seven cervical vertebrae are absent or fused, resulting in a short neck with limited range of motion. Classification of Klippel-Feil Syndrome. Type I. Massive fusion of the cervical spine. Type II Orthopedic surgery for cervical torticollis poses potential threat to airway management both in tracheal intubation and extubation. Klippel-Feil syndrome (KFS) is a complex syndrome of osseous and visceral anomalies. The anatomical characteristics of KFS might have significant implications for airway management. This is a rare case of an 8-year-old boy presenting with osseous torticollis. Klippel-Feil syndrome is a rare skeletal anomaly characterised by abnormal fusion of two or more vertebrae. This abnormal fusion occurs with or without additional spinal or extraspinal manifestations. Features include a short neck, restricted mobility of the upper spine and a low hairline. Any of the cervical vertebrae can be involved but the. Klippel-Feil syndrome. c. Rheumatoid arthritis. d. Ankylosing spondylitis. e. Iatrogenic fusion. 2. All of the following findings on MRI of the cervical spine may be associated with Klippel-Feil syndrome except: a. Basilar invagination. b. Congenitally absent cervical pedicle. c. Degenerative disk disease. d. Syringomyelia. 3
Elongated styloid process (eagle's syndrome): Klippel feil syndrome (kfs) is a congenital malformation defined by segmentation failure at one or multiple levels of the cervical spine, with or without thoracic and lumbar segmentation anomalies. Patients whose clinico‐radiological constellations initially implied the diagnosis of Le syndrome de Klippel-Feil est un syndrome d'origine inconnue et rare. On estime qu'une personne sur 42 000 est concernée. Outre la présence d'un cou plus court voire absent, d'autres symptômes peuvent être associés, par exemple des douleurs ou des raideurs cervicales The unusual presentation and radiological findings in a patient with Klippel-Feil syndrome prompted this report. AB - During the neurological work-up of a young patient with Klippel-Feil syndrome, the presence of a neuroschisis of the cervical spinal cord was detected. The patient presented with a transient and acute hemisensory loss and a.
Klippel-Feil Syndrome is a rare spinal birth defect in which two or more of the seven vertebrae or joints in the neck are fused together. It occurs in the early weeks of fetal development and may be sporadic or genetic.. KFS is primarily musculoskeletal, but due to the wide range of potentially associated conditions, it may affect many other parts of the body, including the heart, kidneys. Cavendish ME. Congenital elevation of the scapula. J Bone Joint Surg Br. Aug 1972;54(3):395-408.. Cho TJ, Choi IH, Chung CY, Hwang JK. The Sprengel deformity. Morphometric analysis using 3D-CT and its clinical relevance. J Bone Joint Surg Br. Jul 2000;82(5):711-8. Offiah, AC and Hall CM.Skeletal Radiology in Children: Non-traumatic and Non-malignant, Localized Disorders of the Skeleton
The knowledge of Klippel-Feil syndrome may be of importance to neurosurgeons, radiologists, physical therapists, and orthopedic surgeons dealing with the pathologies of cervical spine. Awareness of the presence or absence of such a fusion, as demonstrated on lateral cervical radiographs, may be of value to the neurosurgeon planning the. Read Klippel-Feil syndrome with cervical diastematomyelia in an 8-year-old boy, Pediatric Radiology on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips
Klippel-Feil syndrome is caused due to mutations of the GDF3 and GDF6 genes present in the long arm of chromosome 8. Mutations of the above listed genes may not occur in a few individuals affected by Klippel-Feil syndrome. In such cases, the cause of the disease is unknown Klippel-Feil syndrome (KFS) is is a rare syndrome that characterized by fusion of at least two congenital verte-brae in the cervical region. The most common charac- Radiological examination of the C4-5 and C6-7 cer-vical region revealed the loss of inteverebral disc spaces and block vertebra. Also there was hemivertebra anomal Background Klippel-Feil anomaly (KFA) can be seen in a number of syndromes. We describe an apparently novel syndromic association with KFA. Methods Clinical phenotyping of two consanguineous families followed by combined autozygome/exome analysis. Results Two patients from two apparently unrelated families shared a strikingly similar phenotype characterised by KFA, myopathy, mild short stature. We present the second case of Klippel-Feil syndrome in association with a posterior fossa dermoid cyst extending through the occipital bone and presenting as a suboccipital subcutaneous mass. We describe its radiographic, CT, and MRI appearances as well as on MRI diffusion-weighted images. Posterior cranial fossa dermoid cysts and sinuses should be added to the list of congenital abnormalities.
Orthopedic Surgery Orthopedic Musculoskeletal Radiology Solve exciting clinical cases specific to your field of interest via Docplexus clinical case challenge. In todays ' Orthopedic Case Challenge' , join your fellow doctors to discuss and answer today's question which is about Klippel-Feil Syndrome Le syndrome de Klippel-Feil (SKF) est caractérisé par un défaut de segmentation des somites cervicaux, résultant en une fusion congénitale de vertèbres cervicales.La prévalence est estimée à 1 sur 50 000. Décrit pour la première fois en 1912 par Maurice Klippel et André Feil en France [1], il est volontiers associé à la triade clinique classique : implantation postérieure basse. Klippel-Feil syndrome (KFS), also known as cervical vertebral fusion syndrome, is a rare congenital condition characterized by the abnormal fusion of any two of the seven bones in the neck (cervical vertebrae).: 578 It results in a limited ability to move the neck and shortness of the neck, resulting in the appearance of a low hairline Klippel-Feil Syndrome is a rare disorder characterized by the congenital fusion of any 2 of the 7 cervical (neck) vertebrae. It is caused by a failure in the normal segmentation or division of the cervical vertebrae during the early weeks of fetal development. The most common signs of the disorder are short neck, low hairline at the back of the.
Oct 28, 2015 - Chest X-ray is recommended to assess other features of Klippel-Feil syndrome: e.g. Sprengel's deformity, omovertebral bone. An ultrasound abdomen to assess possible associated renal anomalies This study shows a Chiari I malformation classifie.. Congenital vertebral malformation (CVM) is a birth defect of the vertebral column with an estimated prevalence of 0.13-0.51 per 1,000 live births (Giampietro et al. 2009. PubMed ID: 19154516). It can be further divided into several groups such as Klippel-Feil syndrome and Spondylocostal Dysostosis. Fetal ultrasound can detect vertebrae defects as early as 13 weeks gestation (Turnpenny et al. 2017 Klippel-Feil Syndrome: Specific Diseases/Disorders [home, info] Klippel-Feil syndrome: Collaborative Hypertext of Radiology [home, info] Klippel-Feil Syndrome: Disorder Index [home, info] Klippel-Feil syndrome: Parents' Common Sense Encyclopedia [home, info] Klippel-Feil syndrome, Klippel Feil syndrome: Medical dictionary [home, info
Klippel-Feil Syndrome (KFS) is a rare congenital disorder which was discovered in 1912 by two French scientists named Maurice Klippel and Andre Feil when they performed an autopsy on an individual with this condition. Thereafter, they discovered 13 other patients with this disorder and published their findings from this group in 1919 Klippel-Feil Syndrome is a rare disorder characterized by the congenital fusion of any 2 of the 7 cervical (neck) vertebrae. It is caused by a failure in the normal segmentation or division of the cervical vertebrae during the early weeks of fetal development. The most common signs of the disorder are short neck, low hairline at the back of the head, and restricted mobility of the upper spine These somites develop soon after inception and start forming the vertebra by separating at about 3-8 weeks of development. Klippel Feil Syndrome is a failure of segmentation of one or more of these somites in the neck. In other words, the segments don't separate. This causes, in effect a fusion of the two cervical vertebral segments Klippel-Feil syndrome is a genetic disorder of the spine that is present at birth, it presents with two or more vertebrae in the upper spinal column fused together, We use cookies to personalize content and ads, to provide social media features, and to analyze our traffic. By continuing to use our site, you accept our use of cookies Klippel-Feil syndrome (KFS) itself is not considered a life-limiting diagnosis. However, the impact of KFS on life expectancy varies depending on the medical issues and how severe they are in a specific person with KFS. In general, people with mild KFS and minimal health issues can lead normal, active lives without major restrictions